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Hydroxycut and Liver Health: Understanding the Risks

Hydroxycut and Liver Health: Understanding the Risks
Meghan Delaney

By Meghan Delaney

April 16, 2025


The weight loss supplement Hydroxycut, once marketed as a “fat burner” by Iovate Health Sciences, came under scrutiny after reports emerged linking its use to severe liver injuries. A case series outlined potential hepatotoxic effects, including instances of acute liver failure that resulted in liver transplantation and even death. Symptoms commonly reported included jaundice, fatigue, nausea, and abdominal pain. Despite the recall of Hydroxycut products in 2009, questions about its safety continue to arise. The supplement's formulation, once including components like ephedra, Garcinia cambogia, and green tea extract, has been associated with hepatocellular injury patterns. These case reports highlight the need for caution when using dietary supplements that are considered capable of causing severe hepatic toxicity. The study underscores the importance of rigorous evaluation and monitoring of supplement ingredients to prevent adverse health outcomes.



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Meghan Delaney

Meghan Delaney

Meghan Delaney is a Denver-based editor and wellness columnist with a background in herbal medicine and mind-body therapies. She’s contributed to Modern Naturalist, Organic Authority, and Gaia Health Journal, focusing on plant-based healing and emotional resilience.


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